What are the currently available antiretroviral drugs(ARVs) and drug classes?
Currently available antiretroviral drugs (ARVs) belong to one of six different drug classes: (i) Nucleoside reverse transcriptase (RT) inhibitors (NRTIs), (ii) Non-nucleoside RT inhibitors (NNRTIs), (iii) Protease inhibitors (PIs), (iv) Integrase inhibitors (INIs), (v) Fusion inhibitors, and (vi) CCR5 inhibitors. There is currently one FDA-licensed INI, one FDA-licensed fusion inhibitor, and one FDA-licensed CCR5 inhibitor. However, there are additional INIs and CCR5 inhibitors in advanced clinical trials. A complete listing of all approved ARVs, their drug class (or mechanism of action), date of FDA licensing, generic name, trade name, and common abbreviations can be found here (I have a page with a complete table).
