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This seems like it would have an effect somewhat similar (although still very different) to that of a "speedball" (cocaine + heroin). The meth would take effect too, and as the meth high is starting to decrease, the vicodin would take effect. Given that meth gives a much longer high than cocaine, you would likely experience the vicodin and meth at the same time.
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What are the effects of taking Vicodin while smoking meth?
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