What are the health benefits of drinking apple juice?
Gain-of-function mutations in the presenilin-1 (PS-1) promote Alzheimer’s disease (AD) by increasing reactive oxygen species, at least part of which is derived by an accompanying increase in generation of amyloid-beta (Abeta). Supplementation with apple juice concentrate was observed to attenuate or prevent the increase of PS-1 expression in juvenile and adult normal mice. [2] Apple juice containing high amounts of antioxidative polyphenols might protect the intestine against oxidative cell damage. [3] [1] “Cloudy” apple juice packs more antioxidants Reuters, Jan 15, 2007. Journal of the Science of Food and Agriculture, online January 15, 2005. [2] Chan A, Shea TB. Supplementation with apple juice attenuates presenilin-1 overexpression during dietary and genetically-induced oxidative stress. J Alzheimers Dis. 2006 Dec;10(4):353-8 [3] Schaefer S, et al, Polyphenolic apple juice extracts and their major constituents reduce oxidative damage in human colon cell lines. Mol Nutr Food Res.
