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What are the phases of CML?

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What are the phases of CML?

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The three phases are: • Chronic phase: This phase may last for about 4 to 5 years. Initially, patients in this phase usually have minor symptoms and their cancer is usually detected by routine blood tests. Traditionally, most patients have received interferon therapy alone or with other drugs. Patients can also be treated with bone marrow transplants. • Accelerated phase: This phase may last from 6 to 18 months. The white blood cell count increases and the disease is harder to control with conventional treatments. • Myeloid blast crisis: This phase is the final phase of the disease and may last about 3 to 6 months. CML worsens as it progresses from the chronic phase to the accelerated phase and the final phase called the blast crisis. The three phases are characterized by steadily increasing numbers of abnormal cells within the bone marrow and by spread of abnormal cells to sites outside of the bone marrow.

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