What are the risk factors for hepatocellular carcinoma?
This cancer usually occurs in people who have chronic scarring of the liver, called cirrhosis. Most commonly, this is caused by chronic infection from one of two viruses: hepatitis B and hepatitis C. Alcohol abuse also increases the risk of developing cirrhosis. Some inherited diseases, especially a disorder called hemochromatosis (in which the body absorbs too much iron), can cause cirrhosis and, in time, hepatocellular carcinoma.
- Are both PIVKA-II and alpha-fetoprotein necessary in follow-up management after hepatic resection for hepatocellular carcinoma?
- Does hepatic vein outflow obstruction contribute to the pathogenesis of hepatocellular carcinoma?
- Is the p53 gene mutation of prognostic value in hepatocellular carcinoma after resection?