What causes a low neutrophil count?
Neutrophils die continuously from age or from fighting infections, and your bone marrow must make new neutrophils to replace them. When something reduces production of neutrophils in your bone marrow, the neutrophil count will drop and may become dangerously low. Prescription medications, such as trimethoprim-sulfamethoxazole (TMP-SMX, Bactrim, Septra), ganciclovir, zidovudine (AZT), interferon, pyrimethamine, primaquine, and many chemotherapy agents used for Kaposis’ sarcoma and lymphoma are common causes of neutropenia. In almost all cases, drug-induced neutropenia (low white count) resolves after the agent is stopped or its dosage is reduced. Drugs that Help Low White Count Neupogen (G-CSF): a colony stimulating factor (CSF)that signals the bone marrow to increase output of white cells (specifically neutrophils), which help to fight bacterial infections. Neulasta: a protein that stimulates the production on white blood cells. Neutropenia during combination therapy of interferon alfa