What clinical research is under way to prevent type 1 diabetes?
The Diabetes Prevention Trial-Type 1 (DPT-1), a large multicenter clinical trial supported by the National Institutes of Health, the American Diabetes Association, and the Juvenile Diabetes Research Foundation International, is applying new knowledge to try to prevent type 1 diabetes in people at risk. DPT-1 is now testing whether oral insulin can prevent type 1 diabetes in people at moderate (25-50 percent) risk of developing type 1 diabetes within 5 years. The same study group recently completed a separate trial which found that low-dose insulin injections do not prevent type 1 diabetes in people with impaired insulin secretion who have a high (50 percent or greater) risk of developing diabetes in 5 years. The oral insulin trial is testing a totally different scientific approach to preventing type 1 diabetes in people at moderate risk for type 1 diabetes whose insulin production is not yet impaired. What do the results of DPT-1s insulin injection trial mean for people with diabetes a
