What does it mean if in addition my biopsy report also says “high grade prostatic intraepithelial neoplasia”?
“High grade prostatic intraepithelial neoplasia” also referred to as “high grade PIN” has no importance for someone who already has a biopsy that is “atypical” or “suspicious for cancer”. Although high grade PIN is sometimes a precursor to prostate cancer, the atypical findings found in your sample are more worrisome for the risk of cancer on rebiopsy than the finding of high grade PIN.