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What does it mean when there are different cores with different Gleason scores?

April 26, 2017cores different gleason mean scores

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What does it mean when there are different cores with different Gleason scores?

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Different cores may sample different areas of the same tumor or different tumors in the prostate. Because the grade may vary within the same tumor or between different tumors, different samples taken from your prostate may have different Gleason scores. Typically the highest (largest number) Gleason score will be the one used by your doctor in predicting prognosis and deciding therapy.