What factors should be considered in choosing and using OTC epinephrine or ephedrine?
Despite the development of newer medications, epinephrine and ephedrine remain available as OTC medications. The choice of epinephrine or ephedrine should involve consideration of several factors. Most importantly, the asthma should be mild and less frequent, defined as occurring less than once per week and lasting from a few hours to a few days at most. OTC epinephrine or ephedrine is best used under the guidance of a physician. A patient should seek medical attention and prepare to switch to a prescription asthma medication if (1) moderate to severe asthma develops, (2) frequent or regular doses of epinephrine or ephedrine are needed to relieve symptoms, (3) episodes of asthma occur once or more per week, or (4) asthmatic episodes develop at night. OTC epinephrine is available in various concentrations for oral inhalation or as a solution in vaporized form (nebulization). Both forms may or may not contain alcohol or sulfite as preservatives. For example, AsthmaHaler Mist does not con