What genes are responsible for tuberous sclerosis?
Two genes have been identified that can cause tuberous sclerosis. Only one of the genes needs to be affected for tuberous sclerosis to be present. The TSC1 gene is located on chromosome 9 and is called the hamartin gene. The other gene, TSC2, is located on chromosome 16 and is called the tuberin gene. Researchers are now trying to determine what these genes do and how a defect in these genes causes tuberous sclerosis.
