What interstates are accessible in Winston-Salem?
Winston-Salem is located at the intersection of U.S. Highway 52 and Interstate 40 (I-40). Business Interstate 40 runs parallel to I-40 through downtown. Interstate 85 is located just south of Winston-Salem and connects to the city via U.S. Highway 52. Interstate 77 is located one hour west of Winston-Salem, and Interstate 95 is two hours east of Winston-Salem, both are accessed via I-40.