What is Buruli Ulcer?
Buruli ulcer is one of the most neglected tropical diseases. It is caused by a “Mycobacterium ulcerans” bacterial infection, which belongs to the same genus of bacteria that caused leprosy and tuberculosis. The initial stage of the infection is characterized either by small, painless nodules under the skin or larger swollen areas. During this phase, the disease often goes unnoticed or is not considered serious enough to seek medical attention. If untreated, the disease continues on its destructive course and the skin and the subjacent tissue begin to die. In most cases, ulcers form on the arms and legs. Even after extensive treatment with antibiotics, the affected tissue must often be surgically removed. Amputation is necessary in a number of cases. The affected individuals suffer from very painful treatments, long stays in hospital and permanent deformities or amputations.