What is Gamma Aminobutyric Acid (GABA)?

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GABA is another name for the nonessential amino, Gamma-Amino Butyric Acid. First discovered in 1883 in Berlin, GABA is formed from glutamic acid with the help of vitamin B6, and is the most important and widespread inhibitory neurotransmitter in the brain since is found in almost every region of it. In human physiology, a neurotransmitter is characterized as a substance that facilitates the network of communication between nerve cells in the central nervous system (CNS). Just like the amino acids aspartate, glutamate, and glycine, GABA is also another amino acid that is critical in brain functioning. With respect to brain chemistry and brain health, GABA may be among the most important of all nonessential nutrients. GABA is synthesized in the body from another amino acid, glutamic acid. Through the action of the enzyme glutamic acid decarboxylase (GAD), which catalyzes the formation of GABA from glutamic acid, GABA is formed. GAD requires vitamin B6 (pyridoxal phosphate) as a ... more
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