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What is glioblastoma multiforme (GBM)?

gbm glioblastoma multiforme
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What is glioblastoma multiforme (GBM)?

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Glioma (cancer of the glial cells) is the most common type of malignant primary brain tumour (a tumour that originates in the brain). Glioblastoma multiforme (GBM) is the most common and most malignant of the glial tumors. Glioblastomas primarily affect adults, and they are located preferentially in the cerebral hemispheres. Much less commonly, glioblastoma multiforme can affect the brainstem (especially in children) and the spinal cord. Glioblastomas can be classified as primary or secondary. Primary glioblastoma multiforme accounts for the vast majority of cases (60%) in adults older than 50 years. These tumors manifest without clinical or histopathologic evidence of a preexisting, less-malignant precursor lesion), presenting after a short clinical history, usually less than 3 months. Secondary glioblastoma multiformes (40%) typically develop in younger patients of less than 45 years. The time required for this progression varies considerably, ranging from less than 1 year to more th

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