What is in the Safety/Pharmacology section of Epocrates OTC monographs?
The Safety/Pharmacology section of Epocrates OTC monographs includes content related to use in pregnancy and lactation, as well as information about the drug’s metabolism, excretion, and mechanism of action. For most oral combination OTC products, pregnancy risk categories and lactation safety ratings are listed for individual ingredients. For products that are systemically absorbed to a clinically significant extent, specific cytochrome P-450 (CYP450) and other metabolic pathways and effects can be found under the Metabolism header, while the drug’s terminal elimination half-life can be found under the Excretion header. The known or proposed mechanism of therapeutic action is also given in this section. (Most oral combination OTC products refer to the individual standard ingredient monographs for this information, which can be accessed by clicking on their respective links.) In addition, the Safety/Pharmacology section lists the Epocrates subclasses to which the drug belongs. Epocrate
