What is the basis for population statistics in Paternity Testing?
• Each alleged father is assumed to have a prior probability of being the father equal tp 50% (50/50) chance before the testing is completed. The paternity index {PI} for each probe used is a likelihood ratio and is defined as the probability that the alleged father contributed the necessary DNA to the child divided by the probability that a random man contributed the necessary DNA to a child. The PIs for all the probes used are then multiplied together to give a combined paternity index (CPI) value. The probability of paternity (POP) is defined as 1 / (1 +1/CPI) and is multiplied by 100 to give a percentage. If an alleged fathers DNA pattern does not match the childs, then the PI for that probe is 0. What is the Paternity Index and how is it Determined? • The Paternity Index or PI gives the odds that the alleged father with a matching allele is the biological father of the tested child. The frequency of each DNA segment (allele) in the human population varies depending on the size of
Each alleged father is assumed to have a prior probability of being the father equal to 50% (50/50) chance before the testing is completed. The paternity index (PI) for each probe used is a likelihood ratio and is defined as the probability that the alleged father contributed the necessary DNA to the child divided by the probability that a random man contributed the necessary DNA to a child. The PI’s for all the probes used are then multiplied together to give a combined paternity index (CPI) value. The probability of paternity (POP) is defined as 1 / (1 +1/CPI) and is multiplied by 100 to give a percentage. If an alleged father’s DNA pattern does not match the child’s, then the PI for that probe is 0.
Each alleged father is assumed to have a prior probability of being the father equal to 50% (50/50) chance before the testing is completed. The paternity index (PI) for each probe used is a likelihood ratio and is defined as the probability that the alleged father contributed the necessary DNA to the child divided by the probability that a random man contributed the necessary DNA to a child. The PIs for all the probes used are then multiplied together to give a combined paternity index (CPI) value. The probability of paternity (POP) is defined as 1 / (1 +1/CPI) and is multiplied by 100 to give a percentage. If an alleged father’s DNA pattern does not match the childs, then the PI for that probe is 0.
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- What is the basis for population statistics in Paternity Testing?
