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What is the cost of the new DNA dyes?

COST dna dyes
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What is the cost of the new DNA dyes?

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The purchase price of SYBR Gold and SYBR Green is significantly higher than that of EtBr. However, it is important to remember that, for example, SYBR Green is 5 -10 times more sensitive than EtBr and less mutagenic. Many people will consider these advantages sufficient to outweigh the additional cost. Because the new generation of DNA stains are generally 5 – 10 times more sensitive than EtBr, it is possible to load correspondingly less DNA molecular weight standards and PCR reactions. This can result in significant savings. For example, a typical mini-gel with 2 lanes of DNA standards costs a total of about $1.86 if stained with EtBr and $1.43 if stained with SYBR Gold. If the samples loaded onto the gel are PCR reaction products, the use of SYBR Gold can result in savings of over $10 compared with EtBr.

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