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What is the dose limiting side effect for cyclosporine and tacrolimus?

April 26, 2017Cyclosporine dose Limiting tacrolimus

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What is the dose limiting side effect for cyclosporine and tacrolimus?

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I’m not sure there is ONE, they could be different for different patients.. Certainly, acute changes in renal function b/c of afferent vasocontriction is an issue. With tacrolimus, you will see some CNS stuff (like tremor).