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What is the effect of extra column volume for different HPLC instruments on the same method?

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What is the effect of extra column volume for different HPLC instruments on the same method?

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[top] The difference can be very significant. Extra column volume that is hidden in your HPLC system, the fittings, the tubing and the flow cell can greatly impact the efficiency of your method. Click here for an example of the impact. To determine your extra column volume, use the MicroSolv HSQ Kit for HPLC Self Compliance. Easy to use and low cost.

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