What is the extinction coefficient of Amino-Modifier C6 dT and C2 dT?
RESPONSE:The extinction coefficient of DNA at 260nm is around 10,000/mole or 10/mole. The extiction coefficient of Amino-Modifier C6 dT and C2 dT is around 8.7. The synthesis of these monomers does not pass through the deoxynucleoside and this figure is estimated by comparison to dT-CE Phosphoramidite.