What is the first-line treatment for oral candidiasis?
• In immunocompetent people, use topical nystatin, or miconazole for first-line treatment. • In immunocompromised people, high-dose oral fluconazole is generally preferred for first-line treatment. • Predisposing local and systemic risk factors for oral candida should be managed in conjunction with anticandidal treatment. • Chlorhexidine should be used to clean dentures and may be used as an adjunct to topical or oral treatment. • Note: the choice of anticandidal drug treatment may be dictated by local policy or based on advice from a local microbiologist.
