What is the function of mast cell?
Simple: Have a role in allergy and anaphylaxis, plus mast cells play an important protective role by being intimately involved in wound healing and defense against pathogens. Not simple: A mast cell activates inflammation by releasing a variety of chemical substances including histamine, tumor necrosis factor, and interleukins. Mast cells have membrane receptors that bind to bacteria, triggering the release of inflammatory mediators from the mast cell’s cytoplasmic granules. Mast cells also play an important role in allergic reactions. Other receptors on their membranes bind to specific antibodies that, combined with certain antigens, initiate granular release of chemical mediators that cause allergic signs and symptoms.
