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The H1 promoter is human in origin and drives the expression of endogenous cellular rRNA genes. It uses RNA polymerase III and is therefore suitable for transcribing the small cloned sequences that will become the shRNA molecules in the pKD mammalian siRNA expression plasmids.
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millipore.com
/techpublications/tech1/mcproto435
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What is the H1 promoter?
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