What is the HER2/neu oncogene and how does Herceptin help?
In 25 to 30% of women with metastatic breast cancer, there is a genetic alteration in the HER2 gene. HER2/NEU is an oncogene that makes proteins that receives signals from growth hormones. This protein helps tumor cells spread therefore if your tumor is HER/neu positive it may indicate an aggressive tumor. If your tumor is HER/neu positive, you could be eligible for a new treatment that interfers with this gene, called Herceptin. Herceptin is one of a biological class of drugs known as monoclonal antibodies.
