What is the relationship between potassium and hyper- or hypokalemic periodic paralysis?
HPERKALEMIC PERIODIC PARALYSIS Hyperkalemic periodic paralysis attacks of weakness are usually associated with an increase in serum potassium levels (up to 5-6 mmol/L). However, this is not always the case. Potassium levels can be normal during an attack. For this reason a number of experts in the field have recommended that this disorder be called Potassium Sensitive Paralysis. Between episodes the serum potassium is normal. During episodes urinary excretion of potassium is also increased. After an attack, there may be excessive urination and the serum potassium level may actually be low. HYPOKALEMIC PERIODIC PARALYSIS Hypokalemic periodic paralysis attacks are usually accompanied by low potassium, typically less than 3.0 mmol/l. Between episodes of weakness the potassium level is normal. In this disorder, reduced potassium levels contribute to the underlying problem with calcium channels in muscle and render the muscle inexcitable. It is the resultant muscle inexcitability that cause
