What is the reproducibility of NimbleGen DNA methylation analysis arrays?
While not fully validated by NimbleGen scientists, Weber et al. (Nat. Genet. 2007, 39(4):457-466) observed highly reproducible DNA methylation data between biological replicates (R = 0.92 for WI38 cells and R = 0.95 and 0.91 for sperm) when using MeDIP coupled with NimbleGen human promoter arrays.