What is the role of the Large Scale Centers in the PSI program?
Four large-scale centers, all established during the PSI pilot phase, have constructed structural genomics pipelines for the production and structural determination of proteins in a high-throughput operation. Over the 5-year period of PSI-2, these centers are expected to coordinate their efforts to generate more than 4,000 structures of protein families, and thus meet the program’s goals of increasing structural coverage of sequenced genes and providing benefits for the entire biomedical community. The centers will also develop new technologies to improve the pipeline and to increase success rates and lower costs.
