What is the role of vitamin C in increasing iron excretion?
Vitamin C at doses of 2-3 mg/kg/day, given along with desferrioxamine, increases iron excretion by increasing the availability of chelatable iron. However, the dose should not exceed 200 mg/day, as excessive doses may increase iron toxicity. It is better to avoid administration of vitamin C in excessively iron-overloaded patients.
