What is the significance of each of the following terms as they apply to MatTeks in vitro human tissue equivalents?
Normal Cells: Non-transformed cells. MatTek does not use immortalized cell lines. By definition, an immortalized cell line has been transformed, and therefore possesses characteristics that are not desirable in a true in vitro human tissue equivalent. Human Cell-Derived: All MatTek tissue equivalents are derived from human cells. This procedure eliminates the cross-species extrapolation concerns that accompany all work done using non-human cells. Organotypic: MatTek’s production process produces differentiated, multi-layer, 3-D human tissue equivalents that closely resemble those found in vivo. MatTek advances in tissue engineering have made it feasible to use in vitro human tissue equivalents to explore many of the scientific questions that could only be pursued in vivo previously.
Related Questions
- What is the significance of each of the following terms as they apply to MatTeks in vitro human tissue equivalents?
- Can any MatTek in vitro human tissue equivalents be used in Inhaled / Nasal Drug Delivery studies?
- Can any MatTek in vitro human tissue equivalents be used in Transdermal Drug Delivery studies?
