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What is the Smith-Waterman analysis and why is it used on the pKD siRNA sequence?

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What is the Smith-Waterman analysis and why is it used on the pKD siRNA sequence?

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It is very analogous to BLAST homolgy searching. It is a program that is designed to search for sequence homology between the submitted sequence and the specified database. However, unlike BLAST, Smith-Waterman uses algorithms that are more suited for searching out limited homology between a short sequence and a long gene in the database.

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