What issues should I consider before prescribing domperidone?
• Evidence is lacking for the use of domperidone in non-ulcer dyspepsia. • Domperidone is licensed for the relief of nausea and vomiting, epigastric sense of fullness, upper abdominal discomfort, and regurgitation of gastric contents. This indication is licensed for use in adults and in children older than 12 years of age who weigh 35 kg or more: • Domperidone is also available over-the-counter and is licensed for the relief of post-prandial feelings of fullness, nausea, epigastric bloating, and belching that is occasionally accompanied by epigastric discomfort and heartburn. Maximum duration of treatment is 2 weeks. It is licensed for use in those 16 years of age or older. • Dose: • For adults and adolescents (older than 12 years of age and weighing 35 kg or more): 10 mg to 20 mg to be taken three to four times per day. The maximum daily dose is 80 mg: • For those with severe renal impairment, the dose may need to be reduced. • The initial duration of treatment is 4 weeks. People shou
