What kind of samples can be used on NimbleGens DNA methylation arrays?
These arrays are designed to detect differences between a sample enriched for methylated DNA and a control sample, such as total genomic DNA. We recommend samples enriched using affinity-based methods that utilize an anti-5-mC antibody or MBD proteins. We also accept enzyme based methods to detect DNA methylation, such as Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP).
