What Makes a Good Research Pedigree?
To start research on any disorder, we need good research pedigrees. Pedigrees refers to a family cluster of dogs. Good research pedigrees include families of 30 or more dogs, meeting the criteria listed below, with at least 1/3 not affected. Each dog submitted helps build up that good pedigree – you don’t need to submit multiple dogs to help get us there. The unaffecteds are as important as the affecteds, as one of the ways this information is analyzed is to compare the DNA of related dogs that have the disorder with those that do not. Researchers look for: 1. Dogs with a condition that is believed to be inherited (Fanconi, PRA, Hip Dysplasia, IPSID, etc.) 2. First degree relatives of the affected (parents, offspring, full siblings). 3. Any mating partner of the affected whether or not affected themselves to complete the family unit.
