What post-exposure prophylaxis (PEP) measures are currently recommended by the U.S. Public Health Service for HIV and therefore incorporated by reference into 5193?
The recommendations of the U.S. Public Health Service with respect to post-exposure prophylaxis for HIV can be found in the following document: “Centers for Disease Control and Prevention. Public Health Service Guidelines for the Management of Health Care Worker Exposures to HIV and Recommendations for Post-exposure Prophylaxis. MMWR Recommendations and Reports. May 15, 1998. Volume 47, RR-7.” The latest version of the CDC MMWR Recommendations should be consulted. The May 15, 1998 Recommendations state in summary: “Occupational exposures [to blood or OPIM] should be considered urgent medical concerns to ensure timely administration of PEP. Health-care organizations should have protocols that promote prompt reporting (of exposure incidents) and facilitate access to post-exposure care. Recommendations for PEP have been modified to include a basic 4-week regimen of two drugs (zidovudine and lamivudine) for most HIV exposures and an expanded regimen that includes the addition of a protease
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