What treatment is avaliable for pseudoxanthoma elasticum?
(Male, 57) A: Pseudoxanthoma elasticum (PXE) is a rare inherited disorder of the connective tissue. Connective tissues are the structural parts of the body that essentially hold the body’s cells together and form a framework for the body. One of the major parts of connective tissue is a protein named elastin. Elastin gives connective tissue the capability of stretching and returning to the original length like a spring. In PXE, calcium is deposited into the elastic fibres of the connective tissue. These calcium deposits alter the normal function of the connective tissue. PXE results in changes in the skin, eyes and cardiovascular system. The mainstay of treatment for PXE is monitoring for early signs of bleeding in any critical area, such as the stomach or eyes. The patient’s GP can check for signs of bleeding in the stomach or bladder. Regular follow-up with a specialist vascular surgeon and/or cardiologist is needed for those who have cardiovascular problems. Diet and exercise and, i
