Whats the difference between physical and genomic particles?
rAVE vectors are supplied to a minimal concentration of 1 x 1010 genomic particles per ml. This relates to the number of AAV particles that have been successfully packaged with the genome to be delivered. During the AAV packaging process many particles are formed lacking the genomic DNA. These lack the ability to transduce the cells they come into contact with and are therefore non-functional. As a researcher you want functional AAV particles. Therefore at GeneDetect we supply the vector product at a minimal guaranteed concentration of genomic particles. For comparison purposes with our competitors who only quote the number of physical particles they supply our physical particle titers are typically 5 x 1012 to 1 x 1013 physical particles per ml.
