Whats the evidence for infliximab?
There is very little research on infliximab for a slipped disc. We found just one study which looked at 41 people who had sciatica caused by a slipped disc.[1] All the people in the study were thinking about having surgery. Some people in the study were treated with infliximab while the others were given a dummy treatment (a placebo). Infliximab made no difference to people’s leg pain, back pain, sick leave or the need for surgery.References Korhonen T, Karppinen J, Paimela L, et al. The treatment of disc herniation-induced sciatica with infliximab: results of a randomized, controlled, 3-month follow-up study. Spine. 2005; 30: 2724–2728. Glossary placebo A placebo is a ‘pretend’ or dummy treatment that contains no active substances. A placebo is often given to half the people taking part in medical research trials, for comparison with the ‘real’ treatment. It is made to look and taste identical to the drug treatment being tested, so that people in the studies do not know if they are ge