Where do flavonoids accumulate in the tissues?
We know that certain flavonoids might have an affinity for certain tissues: milk thistle for the liver, ginkgo for the brain, hawthorne for the heart and bilberry for the eyes. Flavonoids generally have an affinity for the microcirculation/capillary mesh. We also know that when flavonoids are concurrently administered, vitamin C will last several hours longer, specifically in the adrenal tissues.3 How are flavonoids metabolized? New advances in research have helped to give us a greater understanding about the bioavailability of flavonoids. A whole new body of research is coming from the French and Chinese on the actual mechanism of metabolism of flavonoids. Flavonoids occur in plants and most foods as glycosides, and when you cook down most flavonoid glycosides (with the exception of flavanols catechins and proanthocyanidins), they reach the small intestine intact. However, when we eat them, there is a complex series of steps involved to absorb them efficiently. When flavonoids reach t