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GlaxoSmithKline Plc and Human Genome Sciences Inc. said their experimental lupus drug significantly reduced patients’ symptoms 16 weeks into a yearlong trial, pushing Human Genome shares up 4.9 percent in New York trading. The 865-patient study, known as Bliss-52, found that a higher dose of the Benlysta drug started benefiting patients 16 weeks into the trial. Improvement was sustained for both a higher and lower dose from weeks 24 and 28, respectively, for the duration of the 52-week test, according to data presented today at the Scientific Meeting of the American College of Rheumatology in Philadelphia. Initial trial results released in July found that Benlysta was more effective at easing pain, hair loss and skin rash than a placebo. Human Genome Sciences shares more than tripled to their greatest increase since the stock began trading in 1993 on the data. The positive overview surprised analysts, who cited disappointing earlier clinical trials and a history of failures for treatme
* STORY * PHOTO * Glaxo, Human Genome Drug Worked 16 Weeks Into Study (Update2) Share | Email | Print | A A A By Trista Kelley and Elizabeth Lopatto Oct. 20 (Bloomberg) — GlaxoSmithKline Plc and Human Genome Sciences Inc. said their experimental lupus drug significantly reduced patients’ symptoms 16 weeks into a yearlong trial, pushing Human Genome shares up 4.9 percent in New York trading. The 865-patient study, known as Bliss-52, found that a higher dose of the Benlysta drug started benefiting patients 16 weeks into the trial. Improvement was sustained for both a higher and lower dose from weeks 24 and 28, respectively, for the duration of the 52-week test, according to data presented today at the Scientific Meeting of the American College of Rheumatology in Philadelphia. Initial trial results released in July found that Benlysta was more effective at easing pain, hair loss and skin rash than a placebo. Human Genome Sciences shares more than tripled to their greatest increase since
