Which chemoreceptors control alveolar ventilation in high altitude?
Hi! 1st of all there no Central PO2 receptors.The central chemoreceptors r sensitive to both [H+] n CO2 conc but very sensitive to CO2 concentration in the brain as BBB is freely permeable to CO2.This takes place at normal resting conditions at sea level. At high altitudes wht happens is tht the main drive for ventilation shifts fm CO2 on the central chemoreceptors to a LOW PO2 drive of the peripheral chemoreceptors,causing hyperventilation,this is becos of the fact tht the atmospheric pressure drops fm 760 mm Hg of sea level(the atmospheric pressure determines the Alveolar PO2) at high altitude. I hope tht u got it.