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Which drugs intensify the effect of coumarin derivatives (Vitamin K antagonists)?

April 26, 2017antagonists coumarin derivatives drugs intensify vitamin k

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Which drugs intensify the effect of coumarin derivatives (Vitamin K antagonists)?

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• Pain killers (e.g. acetylsalicylic acid) • Antirheumatics (e.g. Phenylbutazon) • Antibiotics (e.g. Penicillin, Ampicillin, Tetracyclin) • Anticholesteremics (Statine, Fibrate) • Antiarrhythmic agents (e.g. Amiodaron, Chinidin) • Antidepressants (tricyclic antidepressants) • Diuretics (e.g. etacryn acid) • Hypoglycaemic drugs (e.g. sulfonyl carbamides) • Thyroid hormones This list is not comprehensive! Only the most common drug classes and drugs are indicated.