WHICH PATIENTS WITH PRIMARY BILIARY CIRRHOSIS OR PRIMARY SCLEROSING CHOLANGITIS SHOULD UNDERGO ENDOSCOPIC SCREENING FOR ESOPHAGEAL VARICES DETECTION?
AIM: To determine if platelet count, serum albumin, prothrombin time (PT) or serum bilirubin were predictors of detectable esophageal varices in patients with either PBC or PSC. For comparison, individuals with cirrhosis due to chronic viral hepatitis or other non-alcoholic related causes were examined. METHODS: Retrospective review of individuals undergoing screening upper endoscopy for EV at a single center. Esophageal varices were reported as being present or absent. The laboratory parameters examined were from blood tested within 3 months of the procedure. RESULTS: A total of 235 patients with PBC/PSC or of the liver disease control groups, underwent a single screening endoscopy between 1996-2001. 86 individuals had been diagnosed with either PBC or PSC, 104 individuals had cirrhosis due to viral hepatitis and 45 individuals had another form of nonalcohol-related compensated cirrhosis. EV were detected in 26 (30%) of the PBC/PSC group, 38 (37%) of the viral hepatitis group, and 21
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