Why Can Prednisone Be Discontinued Suddenly?
Prednisone is a synthetic steroid hormone. It cannot be stopped abruptly because the adrenal gland, which makes natural steroid hormones for the body, is suppressed by long term prednisone administration. Since some steroids are necessary for life, abruptly stopping prednisone leaves one without any steroids at all, a condition known as Addisonian crisis.