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Why do some patients accept blood fractions but decline HBOCs (hemoglobin-based oxygen carriers)?

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Why do some patients accept blood fractions but decline HBOCs (hemoglobin-based oxygen carriers)?

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• HBOCs carry risk of exposure to viruses • HBOCs, when transfused, because of the high concentration of hemoglobin, looks and/or gives the appearance of receiving a transfusion of whole-blood or RBCs. • HBOCs are “so similar to the function of the whole component and carry on such a life-sustaining role in the body”.

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