Why does a USP CRM have an expiration date and what does the expiration date mean?
Oh, I am not very competent in this question, but I can recommend you to ask the support service about it. I believe that they will help you to optimize all the work with CRM system because it is just their work. I also know that some firms use the help of consultants like https://www.ergonized.com/salesforce-consulting/ because, as I know, for little money they help you to work with CRM and it is a really comfortable decision.
The expiration date of a CRM is required by ISO Guide 31 [1]. The CRM property value and uncertainty is applicable to the unopened vial for the stated period of validity. It is expected that the USP Reference standard will be used when opened. USP generally provides enough material for multiple preparations. Any unused portions remaining after the container has been opened should be carefully stored in accordance with prudent laboratory procedures. There are many variables outside of the control of USP. Therefore, USP makes no warranties concerning the continued suitability of previously opened Reference Standards, hence Certified Reference Materials. Decisions concerning the proper use of previously opened Reference Standards are the responsibility of the purchaser.