Why does the protein look so different from the molecule? Where are the atoms and/or bonds in the protein?
There may be thousands of atoms in any one of the target proteins; it often makes sense to visualize the complete protein structure using “space-fill” representations. In comparison to one of our target proteins containing some 3000+ atoms, an example drug-like molecule being considered may consist of a mere 20-50 atomsimagine how tiny the drug-like molecule would be if we displayed it on screen using the same scale as that for the protein!
