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Why is Exim giving “421 Unexpected log failure, please try later” when receiving an SMTP message with a large number of recipients?

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Why is Exim giving “421 Unexpected log failure, please try later” when receiving an SMTP message with a large number of recipients?

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A0005: You are verifying recipients, and your configuration is one that does a different lookup of some sort for each recipient. Exim keeps lookup files open, in case there are several lookups in the same file. Versions of Exim prior to 2.10 did not limit the number of open files used for this purpose, and your operating system’s maximum per process has been reached. Exim is trying to log the failure to open a file, but cannot open the log file, for the same reason. If upgrading Exim is not immediately possible, you might be able to increase your operating system’s maximum number of open files per process.

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