Why is Glyburide, Metformin prescribed?
Glucovance is used in the treatment of type 2 (noninsulin dependent) diabetes. Diabetes develops when the body’s ability to burn sugar declines and the unused sugar builds up in the bloodstream. Ordinarily, sugar is moved out of the blood and into the body’s cells by the hormone insulin. A buildup occurs when the body either fails to make enough insulin or doesn’t respond to it properly. Glucovance is a combination of 2 drugs—glyburide and metformin—that attack high blood sugar levels in several ways. The glyburide component stimulates the pancreas to produce more insulin and helps the body use it properly. The metformin component also encourages proper insulin utilization, and in addition works to decrease sugar production and absorption. Glucovance is prescribed when diet and exercise prove insufficient to keep blood sugar levels under control. Glucovance can also be combined with other diabetes drugs such as Avandia.