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Why is the ED50 reported as a range?

April 26, 2017ed50 range reported

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Why is the ED50 reported as a range?

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Many cell-based assays exhibit assay to assay variation that is independent of the inherent biological activity of the protein. The ED50 range is derived from multiple independent assays of a given lot. This range then defines the bioactivity specifications for future lots. New lots are always assayed side by side with previous lots to ensure consistency and control for assay to assay variability.